| 引用本文: | 朱仝飞, 李 萍, 孙庆文, 陈日荣, 闫志慧.小花清风藤叶的化学成分研究[J].广西植物,2019,39(4):511-515.[点击复制] |
| ZHU Tongfei, LI Ping, SUN Qingwen, CHEN Jihjung, YAN Zhihui.Chemical constituents from leaves of Sabia parviflora[J].Guihaia,2019,39(4):511-515.[点击复制] |
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| 小花清风藤叶的化学成分研究 |
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朱仝飞1, 2, 李 萍1, 2, 孙庆文3, 陈日荣4, 闫志慧1, 2*
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1. 重庆医药高等专科学校, 重庆 401331;2. 重庆市药物制剂工程技术研究中心, 重庆 401331;3. 贵阳中医学院, 贵阳 550002;4. 阳明大学, 台北 11221
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| 摘要: |
| 对于小花清风藤的化学成分和药理作用的研究目前较少报道,为了阐明小花清风藤的物质基础,该研究对小花清风藤(Sabia parviflora)的干燥叶,采用反复硅胶柱色谱、Sephadex LH-20柱色谱、制备薄层色谱及重结晶等手段进行分离纯化,运用化学分析和波谱学方法鉴定化合物的结构。结果表明:从小花清风藤干燥叶的甲醇超声提取物中进行分离共得到12个化合物,分别为N-反式阿魏酰酪胺(1)、N-顺式阿魏酰酪胺(2)、N-反式-对-香豆酰酪胺(3)、N-顺式-对-香豆酰酪胺(4)、N-反式-对-香豆酰章鱼胺(5)、N-顺式-对-香豆酰章鱼胺(6)、阿魏酸(7)、芹菜素(8)、木犀草素(9)、咖啡酸(10)、5-氧阿朴菲碱(11)、齐墩果酸(12)。其中,化合物2、4-9为首次从清风藤属植物中分离得到,化合物1、3、10为首次从该植物中分离得到。 |
| 关键词: 小花清风藤, 化学成分, 酰胺类生物碱 |
| DOI：10.11931/guihaia.gxzw201803054 |
| 分类号:Q946.91 |
| 文章编号:1000-3142(2019)04-0511-05 |
| 基金项目:国家自然科学基金(81560707); 重庆市卫生计生委中医药科技项目(ZY201702127); 重庆医药高等专科学校自然科学重点项目(ygz2017101)[Supported by the National Natural Science Foundation of China(81560707); Chongqing Municipal Health Planning Committee of Chinese Medicine Science and Technology Program(ZY201702127); Key Program of Natural Science Foundation of Chongqing Medical and Pharmaceutical College(ygz2017101)]。 |
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| Chemical constituents from leaves of Sabia parviflora |
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ZHU Tongfei1, 2, LI Ping1, 2, SUN Qingwen3, CHEN Jihjung4, YAN Zhihui1, 2*
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1. Chongqing Medical and Pharmaceutical College, Chongqing 401331, China;2. Chongqing Engineering Research Center of
Pharmaceutical Sciences, Chongqing 401331, China;3. Guiyang College of Traditional Chinese Medicine,
Guiyang 550025, China;4. Yang-Ming University, Taipei 11221, China
1. Chongqing Medical and Pharmaceutical College, Chongqing 401331, China; 2. Chongqing Engineering Research Center of
Pharmaceutical Sciences, Chongqing 401331, China; 3. Guiyang College of Traditional Chinese Medicine,
Guiyang 550025, China; 4. Yang-Ming University, Taipei 11221, China
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| Abstract: |
| In order to elucidate the material basis of S. parviflora, the constituents of S. parviflora were separated and purified with chromatographic methods and recrystallization. The structures were elucidated by chemical analyses and spectroscopic methods. Twelve compounds were isolated from the leaves of S. parviflora, and they were identified as N-trans-feruloyl tyramine(1), N-cis-feruloyl tyramine(2), N-trans-p-coumaroyl tyramine(3), N-cis-p-coumaroyl tyramine(4), N-trans-p-coumaroyl octopamine(5), N-cis-p-coumaroyl octopamine(6), ferulic acid(7), apigenin(8), luteolin(9), caffeic acid(10), fuseine(11), oleanolic acid(12). Compounds 2, 4-9 were isolated from the plants of Sabia Colelbr. for the first time. Compounds 1, 3, 10 were isolated from the plant for the first time. |
| Key words: Sabia parviflora, chemical constituents, amide alkaloid |
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