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甜茶的毒性研究
廖曼云; 覃国忠;
中国人民解放军第181医院药理室
摘要:
甜茶Rubus suavissimus S.Lee的急性毒性试验证明:动物一次经口(大白鼠小白鼠),的LD50=2413毫克±200毫克/公斤体重,与有关文献规定的“食品急性毒性分级标准”对照,符合低毒物质。 亚急性毒性技术证明:每天给予大白鼠服用大剂量(1/10LD50)甜茶素连续60天,狗每日服用甜茶水提物(人用高限量的25倍),连续三周,结果未见明显毒副作用,一般表现良好,食欲大小便均正常,无松毛、萎糜现象,体重曲线上升,与对照组比P>0.2~0.5,无明显差异,不影响动物正常生长。
关键词:  毒性研究  毒副作用  亚急性毒性  尿素氮含量  经口  生殖能力  SGPT  蓄积中毒  Rubus  代谢障碍  
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