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白木香悬浮培养细胞中2-(2-苯乙基)色酮化合物的诱导形成
何梦玲1,2, 戚树源2, 胡兰娟2   
1.广东药学院 中药学院, 广州 510224;2.中国科学院 华南植物园, 广州 510650
摘要:
白木香是我国生产沉香的唯一植物资源,为研究其中次生代谢产物的生物合成,从国产沉香中分离并鉴定了4种已知的2-(2-苯乙基)色酮化合物,实验中以此作为标准品,以白木香根悬浮培养细胞为材料,黄绿墨耳真菌提取物为诱导子,首次在组织培养物中成功诱导了2-(2-苯乙基)色酮化合物的产生,为研究中药沉香活性成分2-(2-苯乙基)色酮化合物的生物合成建立了一个试验体系。
关键词:  沉香  黄绿墨耳真菌  2-(2-苯乙基)色酮  白木香
DOI:
分类号:Q946
Fund project:
Inducible formation of 2-(2-phenylethyl)chromones in cell suspension culture of Aquilaria sinensis
HE Meng-Ling1,2, QI Shu-Yuan2, HU Lan-Juan2   
1.Department of Chinese Traditional Medicine, Guangdong Pharmaceutical University, Guangzhou 510224, China;2.South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China
Abstract:
Aquilaria sinensis is the only species of Aquilaria in China for agarwood resources and has been recorded as endangered plant since 1992. The present dissertation was undertaken to study the inducible formation of the second metabolites in A.sinensis. Four 2-(2-phenylethyl)chromones existed in agarwood were identified. For the first time, fungal extracts of Menanotus flavolivens elicited the production of these chromones in cell suspension culture of A.sinensis,whereas they were not existing in normal condition. And a cell suspension culture system of A.sinensis was established.
Key words:  agarwood  Menanotus flavoliven  2-(2-phenylethyl)chromone   Aquilaria sinensis
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