特优2号桑叶不同提取物的药效学研究

Pharmacodynamics study of extracts from Superior 2 Folium Mori

关键词:  特优2号桑叶  抗炎  降血糖  抑菌

Key words:  Superior 2 Foliun Mori  anti-inflammation  hypoglycemic  restrain bacteria

摘要:

采用小鼠耳廓肿胀、小鼠腹腔毛细血管通透性、大鼠足趾肿胀和四氧嘧啶致小鼠高血糖等动物模型对广西推广的高产桑叶品种‘特优2号'桑叶的不同提取物开展药效学研究。结果表明:该桑叶醇提取物能明显减轻动物的炎症反应(P<0.01); 水提物及醇提物能明显降低小鼠由于四氧嘧啶引起的高血糖症(P<0.01),对金黄色葡萄球菌、大肠杆菌有一定的抑制作用; 水提醇沉物对大肠杆菌有一定的抑制作用。该文为对特优2号桑叶药效学实验的首次报道

Abstract:

The pharmacodynamics of Superior 2 Foliun Mori(a high-yield Mori species popularizing in Guangxi)was studied by using the models of mice swelling auricles,the penetrating ability of mice abdominal capillaries,the models of welling digits of big mice,and the models of mice high blood glucose caused by alloxan. The results showed that the alcohol extract form the F.Mori could obviously lighten the animal inflammation reactions(P<0.01); the extracts of water and alcohol could obviously lower down the mice high blood glucose caused by alloxan(P<0.01),and restrain golden yellow staphylococci,Escherichia coli in certain extent; the extract of water extracting-alcohol precipitating could also restrain E.coli in certain extent. These pharmacodynamic experiments were the first report for Superior 2 F.Mpri.