苦玄参的化学成分研究

Chemical constituents of Picria fel-terrae

关键词:  苦玄参  化学成分  结构鉴定

Key words:  Picria fel-terrae  chemical constituent  structure identification

摘要:

对广西传统的抗菌消炎药用植物苦玄参进行了化学成分研究,采用柱色谱进行分离纯化,运用波谱法进行了结构解析,共鉴定得到7个化合物。它们分别为:芹菜素(1)、芹菜素-7-O-β-D-葡萄糖酸(2)、芹菜素-7-O-α-L-吡喃鼠李糖基(1→2)-β-D-吡喃葡萄糖酸(3)、迷迭香酸(4)、苦玄参苷Ⅳ(5)、苦玄参苷Ⅹ(6)、阿克替苷(7)。其中化合物2、3、4为首次从该植物中分离得到。

Abstract:

The chemical constituents of traditional medicinal plant Picria fel-terrae were studied,the compounds were isolated by column chromatographys and the structures of the isolated compounds were elucidated by means of spectral analysis. Seven compounds were isolated and identified as apigenin(1),apigenin-7-O-β-D-glucuronide(2),apigenin-7-O-α-L- rhamnopyranosyl(1→2)-β-D-glucuronide(3),rosmarinic acid(4),picfeltarraegenin Ⅳ(5),picfeltarraegenin X(6),and acteoside(7). The compounds 2,3 and 4 were obtained from this plant for the first time.