北部湾海洋植物及其共附生微生物次级代谢产物研究进展(综述)

Research progress on secondary metabolites ofmarine plants and their co-epiphytic microorganisms in the Beibu Gulf

关键词:  北部湾, 海洋植物, 海洋微生物, 次级代谢产物, 生物活性

Key words:  Beibu Gulf, marine plant, marine microorganism, secondary metabolite, biological activity

摘要:

海洋植物及其共附生微生物是海洋生物的重要组成部分,能够产生许多结构新颖、活性独特的次级代谢产物,承担多种生理生态功能。北部湾海洋植物物种资源丰富,据统计,海洋植物有3门43种。该文综述了从2002年起北部湾海洋植物及其共附生微生物次级代谢产物的研究进展,从11种红树植物和7种共附生微生物中获得59个新化合物和35个已知活性化合物,从3种海草植物中获得3个新化合物和7个已知活性化合物,从6种海藻植物和1种共附生微生物中获得25个新化合物和8个已知活性化合物,主要涉及结构类型有萜类、生物碱、黄酮类、甾醇,多数具有良好的抗菌、抗氧化、抗肿瘤、抗炎、增强机体免疫力等功效。在此基础上,进一步提出了北部湾海洋植物研究方向及后续的研究建议。该综述为深入研究和开发利用北部湾海洋植物及其共附生微生物提供了参考。

Abstract:

Marine plants and their co-epiphytic microorganisms are important compositions of marine organisms, and can produce many secondary metabolites with novel structures and unique activities and have various physiological and ecological functions. The Beibu Gulf is rich in marine plant species resources. According to statistics, there are 43 species of marine plants in three phyla. This paper reviews the research progress of the secondary metabolites of marine plants and their co-epiphytic microorganisms in the Beibu Gulf since 2002. A total of 59 new compounds and 35 known active compounds were obtained from 11 species of mangrove plants and seven species of co-epiphytic microorganisms, and three new compounds and seven known active compounds were obtained from three species of seagrass plants. A total of 25 new compounds and eight known active compounds were obtained from six species of algae plants and one species of co-epiphytic microorganism, which mainly involved terpenoids, alkaloids, flavonoids and sterols, most of which had good anti-bacterial, anti-oxidation, anti-tumor, anti-inflammatory and enhancing the body immunity. Based on the above results, further research suggestions are put forward. The review provides a reference for further study and utilization of marine plants and their co-epiphytic microorganisms in the Beibu Gulf.