裸花紫珠提取物及其主要成分抗氧化活性研究

潘争红<sup>1; 2*</sup>; 黄思思<sup>1</sup>; 黄 胜<sup>2; 3</sup>; 颜冬兰<sup>2</sup>; 宁德生<sup>1</sup>; 颜小捷<sup>1</sup>; 李典鹏<sup>1</sup>; 谷陟欣<sup>2</sup>

引用本文:	潘争红, 黄思思, 黄胜, 颜冬兰, 宁德生, 颜小捷, 李典鹏, 谷陟欣.裸花紫珠提取物及其主要成分抗氧化活性研究[J].广西植物,2016,36(9):1107-1111.[点击复制]
	PAN Zheng-Hong, HUANG Si-Si, HUANG Sheng, YAN Dong-Lan, NING De-Sheng, YAN Xiao-Jie, LI Ding-Peng, GU Zhi-Xin.Antioxidant activities of extracts and their main constituents of Callicarpa nudiflora[J].Guihaia,2016,36(9):1107-1111.[点击复制]

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裸花紫珠提取物及其主要成分抗氧化活性研究
潘争红^1,2*, 黄思思¹, 黄胜^2,3, 颜冬兰², 宁德生¹, 颜小捷¹, 李典鹏¹, 谷陟欣²
1. 广西植物功能物质研究与利用重点实验室, 广西壮族自治区中国科学院广西植物研究所, 广西桂林 541006;2. 九芝堂股份有限公司, 长沙 410008;3. 海南九芝堂药业有限公司, 海口 570311

摘要:

裸花紫珠是海南一种道地药材,具有消炎止血的功效。裸花紫珠富含黄酮类和苯乙醇苷类化学成分, 它们已经被证实是天然抗氧化剂的主要来源之一。为了考察裸花紫珠药材的抗氧化活性, 该研究采用DPPH·自由基清除法测定裸花紫珠醇提物、4个不同极性部位(石油醚、乙酸乙酯、正丁醇、水)及其7个主要成分的抗氧化作用。结果表明:裸花紫珠醇提物、醇提物的水部位、正丁醇部位、乙酸乙酯部位和化合物木犀草素、木犀草苷、毛蕊花糖苷具有较强的抗氧化活性,而5-羟基-3,7,3',4'-四甲氧基黄酮的抗氧化活性则较弱。该研究结果为裸花紫珠的保健功能开发提供了依据。

关键词: 裸花紫珠, 提取物, 黄酮, 苯乙醇苷, 抗氧化

DOI：10.11931/guihaia.gxzw201506006

分类号:Q946

文章编号:1000-3142(2016)09-1107-05

基金项目:海南省重大科技专项(ZDZX2013008-01-04); 海南省中药现代化专项(2015ZY20); 广西植物研究所基本业务费项目(桂植业10006); 九芝堂股份有限公司博士后工作站自主项目[Supported by Hainan Key Special Project of Science and Technology(ZDZX2013008-01-04); Hainan Special Project of Modernization of Traditional Chinese Medicine(2015ZY20); Foundamental Research Fund of Guangxi Institute of Botany,Jiuzhitang Co. Ltd. Postdoctoral Workstation Project]。

Antioxidant activities of extracts and their main constituents of Callicarpa nudiflora

PAN Zheng-Hong^1,2*, HUANG Si-Si¹, HUANG Sheng^{2, 3}, YAN Dong-Lan², NING De-Sheng¹, YAN Xiao-Jie¹, LI Ding-Peng¹, GU Zhi-Xin²

1. Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin 541006, China;2. Jiuzhitang Co. Ltd., Changsha 410008, China;3. Hainan Jiuzhitang Pharmaceutical Co. Ltd., Haikou 570311, China

Abstract:

Callicarpa nudiflora is a famous region drug of Hainan Province, which is mainly used as anti-inflammatory and hemostatic agents. The plant is rich in flavonoids and phenylethanoid glycosides, which have been proved to be one of the main source of natural antioxidants. To investigate the antioxidant capacities of C. nudiflora, the authors use DPPH scavenging method to determine the antioxidant activity of different polar extracts of C. nudiflora and its main constituents. The alcohol extract, water fraction, butyl alcohol fraction, ethyl acetate fraction showed strong antioxidant activity. Three main compounds, luteolin, luteolin-7-O-β-D-glucoside and acteoside, possessed significant antioxidant activity while 5-hydroxy-3,7,3',4'-tetramethoxyflavone exhibited weak antioxidant activity. The research will provide the evidence for development of health products of C. nudiflora.

Key words: Callicarpa nudiflora, extract, flavonoid, phenylethanoid glycoside, antioxidant activity