黔产莪术油的品质分析

Quality analysis on Guizhou Zedoary turmeric oil

关键词:  黔产莪术, 挥发油, ICP-0ES, HPLC, 质量控制

Key words:  Guizhou Zedoaria, volatile oil, ICP-0ES, HPLC, quality control

摘要:

该研究应用比重瓶法、折光率测定法、旋光度测法及电感耦合等离子体发射光谱法,分别对莪术油的相对密度、折光率、比旋度、重金属含量进行了测定,同时采用HPLC法测定莪术油中成分含量以及建立指纹图谱进行相似度的比较分析。结果表明:黔产莪术油的相对密度为0.987 0,比旋度为+24.146 8°,折光率为1.509,指纹图谱与中药制剂指纹图谱对照,相似度为0.976,总重金属含量总和<10 mg·kg^-1,砷盐未检测出。检测的各项指标均符合2015版中国药典莪术油项下的相关规定,该研究方法可行、数据可靠。该研究结果确认了黔产莪术油有较高的安全性及良好的品质,可作为药材原料使用,为黔产莪术油的综合开发利用及质量控制提供了科学依据。

Abstract:

This study was conducted refering to the 2015 version of the Chinese Pharmacopoeia Zedoary turmeric oil under the relevant provisions. The relative density, refractive index, specific rotation and the content of heavy metal were determined using the method of pycnometer, refractive index method, optical rotation measurement and inductively coupled plasma emission spectroscopy. HPLC method was used to analyze the content of Zedoary turmeric oil and its fingerprint similarity. The research method was feasible and the data were reliable. The results showed that the relative density of Guizhou Zedoary turmeric oil was 0.987 0, the specific rotation was +24.146 8°, and the refractive index was 1.509. The fingerprint was compared with the fingerprint of traditional Chinese medicine preparations, the similarity was 0.976, and the total heavy metal content was less than 10 mg·kg^-1. Arsenic salt was not detected. The indicators tested are in compliance with the relevant provisions of the 2015 edition of the Chinese Pharmacopoeia Zedoary Oil. The results confirmed that the medicinal Zedoary turmeric oil had high safety and good quality, and could be used as raw material for medicinal materials, which provided the scientific basis for the comprehensive development, utilization and quality control of Zedoary turmeric oil.