鹊肾树树皮的化学成分和抗炎作用研究

陈自占1; $21; 2*; $22; $22; $22; $21; 3; $21; 3

引用本文:	陈自占1，李俊1，2*，吴强2，杨瑞云2，黎露清2，李珊1，3，黄纪国1，3.鹊肾树树皮的化学成分和抗炎作用研究[J].广西植物,2011,(6):849-852.[点击复制]
	CHEN Zi Zhan1， LI Jun1，2*，Wu Qiang2， Yang Rui Yun2， Li Lu Qing2， Li Shan1，3， Huang Ji Guo1，3.Chemical constituents and antiphlogistic activity of the bark of Streblus asper[J].Guihaia,2011,(6):849-852.[点击复制]

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鹊肾树树皮的化学成分和抗炎作用研究
陈自占1，李俊1，2*，吴强2，杨瑞云2，黎露清2，李珊1，3，黄纪国1，3
1.珍稀濒危动植物生态与环境保护教育部重点实验室，广西师范大学环境与资源学院， 广西桂林 541004;2.药用资源化学与药物分子工程教育部重点实验室，广西桂林 541004;3. 广西环境工程与保护评价重点实验室，广西桂林 541004

摘要:

通过药理实验确定了鹊肾树树皮的乙酸乙酯萃取物为抗炎活性部位，并利用色谱技术从该部位中分离得到了7个化合物，通过UV、IR、NMR、MS等现代谱学方法鉴定化合物的结构分别为：丁二酸(1)、6 乙基 5 羟基 2，7 二甲氧基 1，4 萘醌(2)、3β，20 二羟基 5β 孕甾烷(3)、5 羟基麦芽酚(4)、双[5 甲酰基糠基]醚(5)、5 羟甲基糠酸(6)、β 胡萝卜苷(7)。除β 胡萝卜苷，其余6个化合物均为首次从该植物中发现。

关键词: 鹊肾树树皮抗炎化学成分分离鉴定

DOI：

分类号:R914

基金项目:

Chemical constituents and antiphlogistic activity of the bark of Streblus asper

CHEN ZiZhan1， LI Jun1，2*，Wu Qiang2， Yang RuiYun2， Li LuQing2， Li Shan1，3， Huang JiGuo1，3

1.Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection(Ministry of Education of China)， School of Environment and Resource of Guangxi Normal University，Guilin 541004， China;2.Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources(Ministry of Education of China)， Guilin 541004， China;3.3.The Guangxi Key Laboratory of Environment Engineering Protection and Assessment， Guilin 541004， China 1.Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection(Ministry of Education of China)
， School of Environment and Resource of Guangxi Normal University，Guilin 541004， China； 2.Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources(Ministry of Education of China)
， Guilin 541004， China； 3.The Guangxi Key Laboratory of Environment Engineering Protection and Assessment， Guilin 541004， China

Abstract:

The antiphlogistic part of the barks of Streblus asper was investigated through pharmacological experiments. Through the use of chromatographic technology，seven compounds were isolated from the antiphlogistic part of，and their structures were identified by spectroscopic analyses，especially NMR.They are：succinic acid(1)，6 ethyl 5 hydroxy 2，7 dimethoxy 1，4 naphthoquinone(2)，3β，20 dihydroxy 5β pregnanes(3)，5 oxymalto1(4)，bis (5 formyl furfuryl)ether(5)，5 hydroxymethyl furoic acid(6)and β daucosterol(7). All compounds were isolated from this plant for the first time except for β daucosterol.

Key words: bark of Streblus asper antiphlogistic chemical constituents isolation identification