| 摘要: |
| 瓦山锥植物富含植物多酚类成分且资源丰富,目前尚无该植物化学成分及生物活性方面的报道。为了明确瓦山锥的物质基础,为该植物资源的合理开发与可持续利用提供科学依据,该研究采用Sephadex LH-20、Diaion HP20SS、Toyopearl HW-40F等多种柱层析方法对瓦山锥树叶乙醇提取物进行分离纯化,从中得到11个单体化合物,它们的结构经波谱数据分析及文献对照鉴定为没食子酸(1)、咖啡酸(2)、1-(3', 4'-二羟基肉桂酰)-环戊-2,3-二酚(3)、绿原酸(4)、绿原酸甲酯(5)、kaempferol 3-O-β-D-glucuronopyranoside(6)、kaempferol 3-O-{β-D-xylopyranosyl-(1→2)- [α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside}(7)、quercetin 3-O-β-D-glucuronopyranoside(8)、quercetin 3-O-β-glucuronide-6″-methyl ester(9)、芦丁(10)、quercetin 5-O- [α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside(11)。所有化合物均为首次从瓦山锥中分离得到,其中化合物3,7-11为首次从锥属植物中分离得到。 |
| 关键词: 瓦山锥, 化学成分, 结构鉴定, 植物多酚 |
| DOI：10.11931/guihaia.gxzw201910019 |
| 分类号:Q946 |
| 文章编号:1000-3142(2020)05-0648-06 |
| Fund project:国家自然科学基金(21562008); 广西自然科学基金(2018GXNSFAA294033,2018GXNSFAA281078); 广西科技重大专项(桂科AA18118015)[Supported by the National Natural Science Foundation of China(21562008); Guangxi Natural Science Foundation(2018GXNSFAA294033,2018GXNSFAA281078); Science and Technology Major Project of Guangxi(AA18118015)]。 |
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| Chemical constituents from Castanopsis ceratacantha(Ⅰ) |
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LI Siwen1,2, WANG Yafeng2, HE Ruijie2, DAI Tiange1,LI Dianpeng2, HUANG Yonglin2*
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1. Guilin Medical University, Guilin 541004, Guangxi, China;2. Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization,
Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin 541006, Guangxi, China
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| Abstract: |
| Castanopsis ceratacantha contains large amounts of polyphenols and abounds in natural resources, but its chemical constituents and biological activities have not been reported. In order to clarify the chemical basis of the plant and provide scientific basis for the rational development and sustainable utilization of the plant resources. The ethanol extracts of C. ceratacantha were isolated and purified by various chromatographic methods such as Sephadex LH-20, Diaion HP20SS, and Toyopearl HW-40F to yield 11 compounds. Their structures were elucidated by spectroscopic data and comparison with literatures as gallic acid(1), caffeic acid(2), 1-(3',4'-dihydroxycinnamoyl)-cyclopenta-2,3-diol(3), chlorogenic acid(4), chlorogenic acid methyl ester(5), kaempferol 3-O-β-D-glucuronopyranoside(6), kaempferol 3-O-{β-D-xylopyranosyl-(1→2)- [α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside}(7), quercetin 3-O-β-D-glucuronopyranoside(8), quercetin 3-O-β-glucuronide-6″-methyl ester(9), rutin(10), and quercetin 5-O- [α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside(11). All these compounds were obtained from this plant for the first time,and compounds 3, 7-11 were isolated from the genus Castanopsis for the first time. |
| Key words: Castanopsis ceratacantha, chemical constituents, structural identification, polyphenols |
