| 摘要: |
| 为了明确展毛野牡丹的化学成分,该研究采用Diaion HP20SS、MCI gel、Sephadex LH-20柱层析和反相高效液相色谱等方法,对展毛野牡丹根和茎的醇提物分别进行了分离纯化。结果表明:从展毛野牡丹中分离得到11个化合物,它们的结构经波谱数据分析和鉴定。它们分别是4-羟基-3-甲氧基苯酚1-O-β-D-(6'-O-没食子酰)-吡喃葡萄糖苷(1)、3,4-二羟基苯乙醇4-O-β-D-(6'-O-没食子酰基)-吡喃葡萄糖苷(2)、龙胆酸5-O-β-D-(6'-O-没食子酰基)-吡喃葡萄糖苷(3)、2,4,6-三甲氧基苯酚1-O-β-D-(6'-O-没食子酰)-吡喃葡萄糖苷(4)、甲基6-O-没食子酰基-β-D-吡喃葡萄糖苷(5)、乙基6-O-没食子酰基-β-D-吡喃葡萄糖苷(6)、6'-O-没食子酰基黑樱苷(7)、没食子酸甲酯(8)、没食子酸乙酯(9)、2,6-二甲氧基对苯二酚4-O-β-D-吡喃葡萄糖苷(10)、 2-甲氧基对苯二酚4-O-β-D-吡喃葡萄糖苷(11)。所有化合物均为首次从展毛野牡丹中分离得到,化合物2-7、10和11为首次从该属植物中分离得到。 |
| 关键词: 展毛野牡丹, 野牡丹属, 化学成分, 酚类, 结构鉴定 |
| DOI：10.11931/guihaia.gxzw201901038 |
| 分类号:Q946 |
| 文章编号:1000-3142(2020)05-0641-07 |
| Fund project:国家自然科学基金(21562008); 广西自然科学基金(2018GXNSFAA294033,2018GXNSFAA281078); 中国博士后专项基金(200626); 广西植物研究所基本业务费项目(桂植业18004); 广西八桂学者专项项目(第三批); 广西科技重大专项(桂科AA18118015); 广西植物功能物质研究与利用重点实验室开放基金(ZRJJ2016-3,ZRJJ2016-19)[Supported by the National Natural Science Foundation of China(21562008); Guangxi Natural Science Foundation(2018GXNSFAA294033, 2018GXNSFAA281078); China Postdoctoral Science Foundation(200626); Fundamental Research Fund of Guangxi Institute of Botany(18004); Program for Bagui Scholars of Guangxi Institute of Botany(The third batch); Science and Technology Major Project of Guangxi(AA18118015); Open Fund Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization(ZRJJ2016-3, ZRJJ2016-19)]。 |
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| Phenolic constituents from Melastoma normale |
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HE Ruijie, WANG Yafeng, LI Dianpeng, HUANG Yonglin*
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Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guangxi
Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin 541006, Guangxi, China
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| Abstract: |
| To clarify the chemical constituents of Melastoma normale, the ethanol extracts of roots of and stems M. normale were respectively isolated and purified by various chromatographic methods such as Diaion HP20SS, MCI gel, Sephadex LH-20, and reversed-phase HPLC. Eleven compounds were obtained, and their structures were identified by spectral data analyses. They are 4-hydroxy-3-methoxyphenyl 1-O-β-D-(6'-O-galloyol)-glucopyranoside(1), 3,4-dihydroxyphenethyol alcohol 4-O-β-D-(6'-O-galloyol)-glucopyranoside(2), gentisic acid 5-O-β-D-(6'-O-galloyl)-glucopyranoside(3), 2,4,6-trimethoxyphenol 1-O-β-D-(6'-O-galloyl)-glucopyranoside(4), methyl 6-O-galloyl-β-D-glucopyranoside(5), ethyl 6-O-galloyl-β-D-glucopyranoside(6), 6'-O-galloylprunasin(7),methyl gallate(8), ethyl gallate(9), 2,6-dimethoxy-hydroquinone-4-O-β-D-glucopyranoside(10), and 2-methoxy-hydroquinone-4-O-β-D-glucopyranoside(11). All these compounds were obtained firstly from this plant, and compounds 2-7, 10, and 11 were obtained from the genus Melastoma for the first time. |
| Key words: Melastoma normale, Melastoma L., chemical composition, phenolic constituents, structure identification |
