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荔枝草中一个新的倍半萜
陈小英1,2, 刘章彬2, 蒋小华2, 霍华珍2, 李典鹏2, 于 洋2*   
1. 广西中医药大学 药学院, 南宁 530200;2. 广西壮族自治区 中国科学院 广西植物研究所, 广西植物功能物质研究与利用重点实验室, 广西 桂林541006
摘要:
为了研究荔枝草全草中的倍半萜类化学成分,该文运用大孔吸附树脂D101、MCI、硅胶和反相HPLC等色谱技术对其进行分离纯化,根据HR-ESI-MS、NMR波谱数据鉴定了化合物的结构。结果表明:从荔枝草全草95%乙醇提取物的乙酸乙酯部位中分离得到3个桉叶烷型倍半萜类化合物,分别鉴定为8-ethoxy-eudebeiolide B(1)、salplebeone D(2)、salplebeone A(3)。其中,化合物1为新化合物。
关键词:  荔枝草, 倍半萜, 8-ethoxy-eudebeiolide B, salplebeone D, salplebeone A
DOI:10.11931/guihaia.gxzw202005009
分类号:Q946.91
文章编号:1000-3142(2021)11-1850-05
Fund project:广西壮族自治区“八桂学者”专项项目; 中国科学院“西部之光”基金(人字[2018] 6号); 广西科学院基本科研业务费项目(2017YJJ23006); 广西植物功能物质研究与利用重点实验室主任基金(ZRJJ2019-5)[Supported by the Bagui Scholar Program of Guangxi; West Light Foundation of the Chinese Academy of Sciences([2018] 6); Basic Research Fund of Guangxi Academy of Sciences(2017YJJ23006); Fund of Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization(ZRJJ2019-5)]。
A new sesquiterpenoid from Salvia plebeia
CHEN Xiaoying1,2, LIU Zhangbin2, JIANG Xiaohua2, HUO Huazhen2, LI Dianpeng2, YU Yang2*   
1. College of Pharmacy, Guangxi University of Chinese Medicine, Nanning 530200, China;2. Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin 541006, Guangxi, China
Abstract:
Three eudesmane-type sesquiterpenoids were isolated from the ethyl acetate layer of 95% ethanol extract of the whole plants of Salvia plebeia by various chromatographic methods, including macroporous resin D101, MCI, silica gel, and reversed-phase HPLC. Their structures were elucidated as 8-ethoxy-eudebeiolide B(1), salplebeone D(2), and salplebeone A(3)by using HR-ESI-MS and NMR data, in which Compound 1 is a new compound.
Key words:  Salvia plebeia, sesquiterpenoids, 8-ethoxy-eudebeiolide B, salplebeone D, salplebeone A
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