云南红豆杉内生真菌Talaromyces sp.T1BF的化学成分研究

李良群1; 2; $23; $21; $22; $21*

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云南红豆杉内生真菌Talaromyces sp.T1BF的化学成分研究
李良群1，2，杨艳光3，曾英1，邹澄2，赵沛基1*
1.中国科学院昆明植物研究所植物化学和西部资源可持续利用国家重点实验室，昆明 650204;2.昆明医学院药学院暨云南省天然药物药理重点实验室，昆明 650500;3.贵阳医学院，贵阳 550004

摘要:

采用色谱技术从云南红豆杉内生真菌Talaromyces sp.T1BF的PDA平板发酵物中分离得到4个化合物。经波谱数据分析及与文献对照，分别鉴定为5α，6α 环氧 24(R) 甲基胆甾 7，22 二烯 3β 醇(1)、醌茜素(2)、苔色酸(3)和间甲基苯酚(4)。化合物1为首次从该属真菌中分离获得。

关键词: 云南红豆杉内生真菌平板发酵

DOI：

分类号:Q936

Fund project:

Chemical constituents of endophyte Talaromyces sp.T1BF from Taxus yunnanensis

LI LiangQun1，2， YANG YanGuang3， ZENG Ying1， ZOU Cheng2， ZHAO PeiJi1*

1.State Key Laboratory of Phytochemistry and Plant Resourses in West China， Kunming Institute of Botany， Chinese Academy of Sciences， Kunming 650204， China;2.School of Pharmaceutical Sciences， Kunming Medical University， Kunming 650500， China;3.Guiyang Medical University， Guiyang 550004， China

Abstract:

Four compounds were isolated from PDA plate cultures of Talaromyces sp. T1BF，an endophyte from Taxus yunnanensis by chromatography techniques. They were identified as 5α，6α epoxy 24(R) methylcholesta 7，22 dien 3β ol(1)，skyrin(2)，orsellinic acid(3)and m cresol(4)on the basis of spectroscopic data analyses and comparison with literature values. Compound 1 was obtained from the genus of Talaromyces for the first time.

Key words: Taxus yunnanensis endophyte solid cultures