Page 23 - 《广西植物》2025年第10期
P. 23
10 期 周堂等: 昆明山海棠对肿瘤细胞具有毒性的松香烷型二萜类成分 1 7 5 3
triterpenoids from Tripterygium hypoglaucum [ J ]. speed counter ̄current chromatography separation of five
Phytochemistryꎬ 46(3): 535-543. diterpenoids from Triperygium wilfordii and scale ̄up
DUAN HQꎬ TAKAISHI Yꎬ MOMOTA Hꎬ et al.ꎬ 1999. [J]. Journal of Chromatography Aꎬ 1200(2): 129-135.
Immunosuppressive diterpenoids from Tripterygium wilfordii SUN YYꎬ XIAO Lꎬ WANG Dꎬ et al.ꎬ 2017. Triptolide inhibits
[J]. Journal of Natural Productsꎬ 62 (11): 1522-1525. viability and induces apoptosis in liver cancer cells through
GAO Cꎬ WANG Dꎬ ZHANG Yꎬ et al.ꎬ 2016. Kaurane and activation of the tumor suppressor gene p53 [ J ].
abietane diterpenoids from the roots of Tripterygium wilfordii International Journal of Oncologyꎬ 10: 3892.
and their cytotoxic evalution [ J ]. Bioorganic Medicinal TAKAISHI Yꎬ WARIISHI Nꎬ TATEISHI Hꎬ et al.ꎬ 1997.
Chemistry Lettersꎬ 26(12): 2942-2946. Phenolic diterpenes from Tripterygium wilfordii var. regelii
GUO FJꎬ XI MCLꎬ LI YCꎬ 1999. Triptotin A and Bꎬ two novel [J]. Phytochemistryꎬ 45(5): 979-984.
diterpenoids from Tripterygium wilfordii [ J]. Tetrahedron TOZAWA Kꎬ SAGAWA Mꎬ KIZAKI Mꎬ 2011. Quinone
Lettersꎬ 40(5): 947-950. methide tripterineꎬ celastrolꎬ induces apoptosis in human
HAN HYꎬ DU LSꎬ CAO ZFꎬ et al.ꎬ 2018. Triptonide potently myeloma cells via NF ̄κB pathway [J]. International Journal
suppresses pancreatic cancer cell ̄mediated vasculogenic of Oncologyꎬ 39(5): 1117-1122.
mimicry by inhibiting expression of VE ̄cadherin and WANG FFꎬ ZHANG YMꎬ HE Yꎬ et al.ꎬ 2017. Spectral analysis
chemokine ligand 2 genes [ J ]. European Journal of and structural elucidation of Triptophnolide [ J]. Chinese
Pharmacologyꎬ 818: 593-603. Journal of Magnetic Resonanceꎬ 34(1): 35-42. [王菲菲ꎬ
HUANG YFꎬ GONG SJꎬ HUANG Lꎬ et al.ꎬ 2010. Comparative 张聿梅ꎬ 何轶ꎬ 等ꎬ 2017. 雷酚内酯的波谱学数据与结构
study on chemical constituents in roots of Triptergium 确证 [J]. 波谱学杂志ꎬ 34(1): 35-42.]
wilfordii Hook. f. and T. hypoglaucum (Levi.) Hutch. by thin WANG JHꎬ YANG BJꎬ SUN YMꎬ et al.ꎬ 2023. Study on
layer chromatography [J]. Lishizhen Medicine and Materia chemical constituents and anti ̄tumor activity from the root of
Medicaꎬ 21(8): 1973-1974. [黄耀峰ꎬ 龚受基ꎬ 黄林ꎬ 等ꎬ Tripterygium hypoglaucum [ J]. Journal of Yunnan Minzu
2010. 雷公藤和昆明山海棠植物根中化学成分的薄层色 University (Natural Sciences Edition)ꎬ 32(2): 1-10. [王
谱对比研究 [J]. 时珍国医国药ꎬ 21(8): 1973-1974.] 计宏ꎬ 杨碧娟ꎬ 孙玉梅ꎬ 等ꎬ 2023. 昆明山海棠根茎的化
JANG SYꎬ JANG SWꎬ KO Jꎬ 2011. Celastrol inhibits the 学成分及其抗肿瘤活性研究 [J]. 云南民族大学学报 (自
growth of estrogen positive human breast cancer cells through 然科学版)ꎬ 32(2): 1-10.]
modulation of estrogen receptor α [ J]. Cancer Lettersꎬ WANG YSꎬ HUANG Rꎬ YANG JHꎬ et al.ꎬ 2010. Research
300(1): 57-65. progress on chemical constituents of Triptery giumwil fordii
LUO YYꎬ SHI JFꎬ CHEN Lꎬ et al.ꎬ 2019. Research progress on Hook. f. [J]. Chinese Traditional and Herbal Drugsꎬ 41(8):
triptolide functionalized nanoparticulate drug delivery systems 1252-1254. [汪云松ꎬ 黄荣ꎬ 杨靖华ꎬ 等ꎬ 2010. 火把花二
for tumor treatment [J]. China Journal of Chinese Materia 萜化学成分研究 [J]. 中草药ꎬ 41(8): 1252-1254.]
Medicaꎬ 44(21): 4566-4572. [罗尧尧ꎬ 石金凤ꎬ 陈梁ꎬ XIE CQꎬ 2016. Study on effective substance basis and action
等ꎬ 2019. 雷公藤甲素功能化纳米递药系统用于抗肿瘤的 mechanism of Tripterygium hypoglaucum ( Levl.) Hutch
研究进展 [J]. 中国中药杂志ꎬ 44(21): 4566-4572.] based on activity of anti ̄multidrug resistance cancer
MIYATA Yꎬ SATO Tꎬ ITO Aꎬ 2005. Triptolideꎬ a diterpenoid [D]. Nanjing: Nanjing University of Chinese Medicine. [谢
triepoxideꎬ induces antitumor proliferation via activation of c ̄ 晨琼ꎬ 2016. 基于抗多药耐药肿瘤活性导向的昆明山海棠
Jun NH  ̄terminal kinase 1 by decreasing phosphatidylinositol 药效物质基础及作用机制研究 [D]. 南京: 南京中医药
2
3 ̄kinase activity in human tumor cells [J]. Biochemical and 大学.]
Biophysical Research Communicationsꎬ 336(4): 1081-1086. XU JZꎬ LU Jꎬ SUN Fꎬ et al.ꎬ 2011. Terpenoids from
MOROTA Tꎬ OGINO Tꎬ KATSYHARA Kꎬ et al.ꎬ 1995. D: A ̄ Tripterygium wilfordii [ J ]. Phytochemistryꎬ 72(11):
friedo ̄24 ̄noroleanane triterpenoids from Tripterigium 1482-1487.
wilfordii [J]. Phytochemistryꎬ 40(3): 865-870. YU XLꎬ ZHOU Xꎬ FU CLꎬ et alꎬ 2015. Celastrol induces
NI Lꎬ MA Jꎬ LI CJꎬ et al.ꎬ 2015. Novel rearranged and highly apoptosis of human osteosarcoma cells via the mitochondrial
oxygenated abietane diterpenoids from the leaves of apoptotic pathway [ J ]. Oncology Reportsꎬ 34(3):
Tripterygium wilfordii [ J]. Tetrahedron Lettersꎬ 56 (10): 1129-1136.
1239-1243. YUAN SQꎬ WANG LPꎬ CHEN XXꎬ et al.ꎬ 2020. Corrigendum
PAN ZJꎬ LI ZWꎬ ZHANG ZH et al.ꎬ 2016. Research progress to triptolide inhibits the migration and invasion of human
on chemical composition and activity of THH [J]. Applied prostate cancer cells via Caveolin ̄1/ CD147/ MMPs pathway
Chemical Industryꎬ 45(增刊 2): 8-10ꎬ 14. [盘振杰ꎬ 李志 [J]. Biomedicine & Pharmacotherapyꎬ 122: 109782.
文ꎬ 张钊华ꎬ 等ꎬ 2016. 昆明山海棠的化学成分及活性研
究进展 [J]. 应用化工ꎬ 45(Suppl. 2): 8-10ꎬ 14.] (责任编辑 周翠鸣)
PENG AHꎬ LI Rꎬ HU Jꎬ et al.ꎬ 2008. Flow rate gradient high ̄

